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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1E All Species: 21.21
Human Site: S2141 Identified Species: 46.67
UniProt: Q15878 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15878 NP_000712.2 2313 261731 S2141 G T G S L S E S S I P S V S D
Chimpanzee Pan troglodytes XP_520396 2784 310342 S2566 R R Q P S S S S S E K Q R F Y
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 S2138 G T G S L S E S S I P S V S D
Dog Lupus familis XP_547425 2465 277756 S2283 G T G S L S E S S I P S I S D
Cat Felis silvestris
Mouse Mus musculus Q61290 2272 257217 S2101 G T G S L S E S S I P S I S D
Rat Rattus norvegicus Q07652 2222 252098 S2050 G T G S L S E S S I P S I S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 T2023 T P P N R D H T P Y Y T P L I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 S1666 E M D A M K E S I E A K F I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 I1688 L A S R R A G I G R R L P P T
Honey Bee Apis mellifera NP_001159376 1904 215872 I1741 P A R T P S P I H H I D R G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 E1803 S S E R M D P E S S Q S S P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.8 95.8 90.7 N.A. 94.6 92.5 N.A. N.A. 26.4 N.A. 20.4 N.A. 43.5 46.2 N.A. 39.5
Protein Similarity: 100 57.8 96.3 92 N.A. 95.8 93.8 N.A. N.A. 41.9 N.A. 37.4 N.A. 55.8 57.8 N.A. 52.5
P-Site Identity: 100 20 100 93.3 N.A. 93.3 93.3 N.A. N.A. 0 N.A. 13.3 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 20 N.A. 26.6 N.A. 6.6 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 10 0 10 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 19 0 0 0 0 0 10 0 0 46 % D
% Glu: 10 0 10 0 0 0 55 10 0 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 46 0 46 0 0 0 10 0 10 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 19 10 46 10 0 28 10 10 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 0 % K
% Leu: 10 0 0 0 46 0 0 0 0 0 0 10 0 10 0 % L
% Met: 0 10 0 0 19 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 10 10 10 0 19 0 10 0 46 0 19 19 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % Q
% Arg: 10 10 10 19 19 0 0 0 0 10 10 0 19 0 10 % R
% Ser: 10 10 10 46 10 64 10 64 64 10 0 55 10 46 0 % S
% Thr: 10 46 0 10 0 0 0 10 0 0 0 10 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _